Un-Growth Hormone May Reverse Some Aging

December 24, 2010 8:16 am 1 comment

The good news, this Christmas, is that researchers have found that a compound that acts the opposite way that growth hormones act can reverse some signs of aging. The bad news is that the same research suggests that people who take a growth hormone to stay young may be doing more harm than good. Science Daily reports that the research, conducted at the University of St. Louis, found that in studies involving mice, compound MZ-5-156 had positive effects on oxidative stress in the brain, improving cognition, telomerase activity and life span, while decreasing tumor activity. MZ-5-156 is described as a "growth hormone-releasing hormone (GHRH) antagonist." The researchers also found that MZ-5-156, like many GHRH antagonists, inhibited several human cancers, including prostate, breast, brain and lung cancers. It also had positive effects on learning, and reversed cognitive impairment in the aging mice.

Read an abstract from the study here.

Read more in Science Daily.

1 Comment

  • Article suggests that there are negative effects from taking this growth hormone, but none were identified. Please revise to include primary negative aspects, as presently identified.

Leave a Reply


Recent Posts

  • Fitness Pain More Exercise = More Tolerance For Pain

    More Exercise = More Tolerance For Pain

    It’s not news, as Gretchen Reynolds writes in the New York Times, that our tolerance for pain increases when we exercise–and she means at the time we exercise. Everyone knows that. But it is news, as she reports, that exercise has been shown to increase our tolerance for pain in the long term. Reynolds directs our attention to a study done at University of New South Wales and Neuroscience Research Australia and published in Medicine & Science in Sports & […]

    Read more →
  • Fitness Pain Running For Fitness: Stop At 30 Miles Per Week

    Running For Fitness: Stop At 30 Miles Per Week

    OK, the first thing to consider is that this study was done with heart-attack survivors. The second thing to know is there are plenty of studies that contradict its findings. What ev, here we go. Researchers at the Lawrence Berkeley National Laboratory and at Hartford Hospital studied the relationship between exercise and cardiovascular disease-related deaths in about 2,400 physically active heart-attack survivors, using the National Walkers’ and Runners’ Health Studies databases. What did they find? A reduction of cardiovascular events of up to […]

    Read more →
  • Pain Women's Health How To Brush Your Teeth: Nobody Really Knows

    How To Brush Your Teeth: Nobody Really Knows

    Looking for some advice on how to brush your teeth? The more people you ask, the more different answers you are likely to get. That’s what researchers at University College in London learned when they looked at the brushing advice given by dental associations across ten countries, toothpaste and toothbrush companies and in dental textbooks. The research revealed what is described as “no clear consensus between the various sources, and a worrying lack of agreement between advice from dental associations […]

    Read more →
  • Gear How To Buy Running Shoes: An Authoritative Guide

    How To Buy Running Shoes: An Authoritative Guide

    How hard is it to buy running shoes? Slightly less hard than buying craft beer is these days, but only slightly. Fortunately, runners have the American College of Sports Medicine to turn to for advice, lots of advice. Look, here’s some now: The college recommends that a running shoe have “minimal heel-to-toe drop: This drop is the difference in the thickness of the heel cushion to the thickness in the forefoot cushion area. Shoes with no drop or a small […]

    Read more →
  • Fitness Pain Sex Cycling May Increase Prostate Cancer Risk. Or Not.

    Cycling May Increase Prostate Cancer Risk. Or Not.

    That’s right. Cycling may increase the risk of prostate cancer. Or, it may not. How helpful is that knowledge, which comes from a study at University College in London, where researchers took a hard look at the cycling habits and health of more than 5,000 male cyclists? The good news: the study appeared to disprove the suggestions of some research that cycling increases the risk of impotence and infertility. The possibly bad news: the men who biked the most, more […]

    Read more →
  • Pain Shin Splints. Funny Name, But Not Fun

    Shin Splints. Funny Name, But Not Fun

    Shin splints sound like the kind of thing that might be amusing, at least until you learn that their technical name is medial tibial stress syndrome. Ouch! That hurts, and shin splints can hurt for a long time, up to six months, according to this piece in the Los Angeles Times.  The Times tell us that the “stress” in “medial tibial stress syndrome” is exerted on the soft tissue surrounding the tibia, and that tissue becomes inflamed. What causes them? […]

    Read more →
  • Attitude Pain Men Would Rather Hurt Themselves Than Be Alone With Their Thoughts

    Men Would Rather Hurt Themselves Than Be Alone With Their Thoughts

    Apparently, it really does hurt to think. And researchers at the University of Virginia and Harvard have demonstrated just how much it can hurt, in a series of experiments that asked people to sit alone with their thoughts. A UVA news release reports that the researchers found that study participants did not enjoy spending even brief periods of time alone in a room with nothing to do but think, ponder or daydream. Most preferred listening to music or using a […]

    Read more →
  • Attitude Pain Another Medical Thing You Don’t Really Need: A Pelvic Exam

    Another Medical Thing You Don’t Really Need: A Pelvic Exam

    We are moving, slowly, toward the day when evidenced-based medicine is more than a buzzword. The latest victim of efforts to distinguish medical practices that actually do something good from those that just cost money and cause pain is the pelvic exam, declared unnecessary in guidelines issued last week by the American College of Physicians. The Wall Street Journal reports that the College examined research published from 1946 to 2014 that studied the effectiveness of the pelvic exam, and found […]

    Read more →