Un-Growth Hormone May Reverse Some Aging

December 24, 2010 8:16 am 1 comment

The good news, this Christmas, is that researchers have found that a compound that acts the opposite way that growth hormones act can reverse some signs of aging. The bad news is that the same research suggests that people who take a growth hormone to stay young may be doing more harm than good. Science Daily reports that the research, conducted at the University of St. Louis, found that in studies involving mice, compound MZ-5-156 had positive effects on oxidative stress in the brain, improving cognition, telomerase activity and life span, while decreasing tumor activity. MZ-5-156 is described as a "growth hormone-releasing hormone (GHRH) antagonist." The researchers also found that MZ-5-156, like many GHRH antagonists, inhibited several human cancers, including prostate, breast, brain and lung cancers. It also had positive effects on learning, and reversed cognitive impairment in the aging mice.

Read an abstract from the study here.

Read more in Science Daily.

1 Comment

  • Article suggests that there are negative effects from taking this growth hormone, but none were identified. Please revise to include primary negative aspects, as presently identified.

Leave a Reply


Recent Posts

  • Fitness Pain Two Ways To Avoid Running Injuries

    Two Ways To Avoid Running Injuries

    Want to know how to avoid some running injuries? Step lightly. That’s the advice coming through New York Times health columnist Gretchen Reynold’s report on research conducted at Harvard Medical School. The researchers followed 249 female runners –all heel-strikers– for two years, recording their injuries and trying to correlate injuries with their impact loads, meaning the force with which their feet hit the ground. Reynolds tells us that during the two-year period, more than 100 runners were injured badly enough to […]

    Read more →
  • Pain Disrupted Body Clock Is Bad For Your Body

    Disrupted Body Clock Is Bad For Your Body

    It’s called circadian misalignment, and it’s more easily understood as a disruption of the body clock, caused by inverted wake and sleep cycles. And yes, experts have known for a while that shift work, which requires workers to be awake when the brain’s circadian clock is expecting sleep, is a risk factor for hypertension, inflammation and cardiovascular disease, but now they have better idea of how all of that works. A news release from the Harvard Medical School reports that researchers […]

    Read more →
  • Attitude Pain Mindfulness Training Reduces Inflammation

    Mindfulness Training Reduces Inflammation

    Why do we like mindfulness more than we like prescription drugs? It’s healthier and the price is right: zero cents. Now come researchers at Carnegie Mellon University with evidence that mindfulness does something that is often done with prescription drugs. It reduces inflammation. A Carnegie Mellon news release reports that mindfulness meditation training, compared to relaxation training, reduces Interleukin-6, an inflammatory health biomarker, in high-stress, unemployed adults. The researchers put 35 job-seeking, stressed adults through either an intensive three-day mindfulness meditation retreat […]

    Read more →
  • Pain Super Bowl Teams Bring Flu SpikeTo Fans

    Super Bowl Teams Bring Flu SpikeTo Fans

    Here’s the bad news about living in a city whose football team is playing in the Super Bowl. You are more likely to get the flu. In fact, the many social events that accompany the championship game have been shown to boost flu-related deaths among people above the age of 65 by 18 percent. Yes, even if your team wins. How do we know? Because, as the Cornell Chronicle reports, researchers at that school analyzed county-level data from 1974 to 2009, […]

    Read more →
  • Fitness Pain Fitness Could Get You Through A Heart Attack

    Fitness Could Get You Through A Heart Attack

    Among the grimmer reasons to get it shape is this news from researchers at Johns Hopkins: higher levels of physical fitness may not only reduce risk of heart attacks and death from all causes, but also possibly improve the chances of survival after a first attack. A Johns Hopkins news release reports that researchers at the school studied the medical records of people who had taken a treadmill stress test before their first heart attack and used the patient’s achieved metabolic equivalent score […]

    Read more →
  • Gear Sweatband Knows When You’re Dehydrated

    Sweatband Knows When You’re Dehydrated

    No, you can’t buy it yet, but somebody is going to take this to the bank. Researchers at UC Berkeley have developed a sweat band that can measure metabolites and electrolytes in sweat, calibrate the data based upon skin temperature and sync the results in real time to a smartphone. A UC Berkeley news release reports that the researchers imagine that their device could alert users to health problems such as fatigue, dehydration and dangerously high body temperatures. Wait, there’s more: The […]

    Read more →
  • Eating Well Fitness Pain Protein Diet Helps Both Muscle Gain and Weight Loss

    Protein Diet Helps Both Muscle Gain and Weight Loss

    Here’s the story: Researchers at McMaster University put 40 young men on a diet with 40 percent of the dietary energy they would normally consume, and also had them suffer through a month of hard exercise. As Science Daily reports, while all of the 40 were on a low calorie diet, half of the group was given more protein than the other half. The bottom line? All of the participants, by virtue of the demanding six-days-a-week exercise routines, got stronger, fitter, […]

    Read more →
  • Pain For Lower Back Pain, Exercise

    For Lower Back Pain, Exercise

    First, the bad news. An academic review of 23 seemingly authoritative studies of back pain relief found that most of them, which involved education or orthotics, did almost nothing to reduce the likelihood of another bout of pain. But as Gretchen Reynolds reports in the New York Times, exercise did do some good. In fact, it did quite a bit of good. Reynolds reports that the researchers found that exercise combined with education reduced the risk of another episode of […]

    Read more →