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Osteoporosis Drugs Do More Harm Than Good

The biggest concern about drugs that treat osteoporosis, the bone weakening disease that is common in post-menopausal women, is that long term use appears to increase the risk of fractures in the thigh bone. The Los Angeles Times reports that a 2008 study first linked long-term use of bisphosphonates (Fosamax, Boniva, Actonel and Reclast) to femur fractures, and other research has confirmed the link. That's why, two weeks ago, the Food and Drug Administration announced it will require bisphosphonate drugs to carry information on their labels describing the risk of rare femur fractures.The Times reports that bisphosphonate have also been linked to  jaw necrosis, a condition in which the jawbone begins to deteriorate a slightly higher risk of developing esophageal cancer. The good news, the paper reports, is that there are other drugs to treat osteoporosis. One is the parathyroid hormone drug teriparatide (sold under the brand name Forteo), which, unlike the bisphosphonates, works by actively building bone. Another is the new medication denosumab (brand name Prolia), which is in a drug class known as the RANK ligand inhibitors.  It's too early to tell if long-term Prolia use causes some of the same side effects as bisphosphonates.

Read more in the Los Angeles Times.

 

 

4 Comments

  1. osterporosis? osteoporosis? which is correct?
    do i have any need for fear being treated for osteoporosis with a weekly Actonel?
    does my wife need to fear annual Reclast treatment for her osteoporosis?

  2. The new labels should read,Side effects-(This Osterporosis Drug Will cause you to get cancer!) Take at you’re on risk! You’re Choise!Drug Does More Harm Than Good. FDA Aproved for you’re Safty.

  3. Aopjrdy.You need to look up heberal treatment for osterporosis on the enter net and see what it sayes and then ash you’re doctor.Don’t stop you’re Med without talking to you’re doctor first.Good luck! And may God Bless.

  4. Sorry about that, I meant herbal treatment.

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