Readers of the Yellow Emperor's Inner Canon, a second century Chinese guide to then-modern medicine, know that acupuncture has been used to kill pain for a very long time. But even currently modern health experts never knew exactly how it kills pain. Until now. And the answer is: adenosine. The Boston Globe reports that researchers at the University of Rochester tested acupuncture in mice, inserting fine needles near their
knees corresponding to points on human charts. The mice had inflamed
paws and the researchers measured their pain response by seeing how
long it took them to withdraw their sore paws from touch or heat. When
the mice had the tiny needles inserted and moved around for 30 minutes,
high levels of the neurotransmitter adenosine were released surrounding
the needle points and their pain was reduced by two-thirds. Adenosine,
which inhibits nerve cells in response to injury, acts like the local
anesthetic lidocaine. The Globe reports that when researchers tried the same trick on
mice that were genetically engineered not to produce adenosine, acupuncture did
not ease their pain. The researchers found that when they gave the
mice a drug that slows down adenosine’s removal from tissue,
the mice had pain relief three times as long as when they had the
treatments without the drug.
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