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Fewer Calories May Slow Aging

Youth may be wasted on the young these days, but researchers at the Pennington Biomedical Research Center at Louisiana State University are hoping to find a way to waste some of it on the rest of us.  The Washington Post reports on a study published in the Journal of the American Medical Association whose results suggest that a low calorie diet can slow down metabolism and lower insulin levels–two processes that are believed to increase longevity. The study, funded by the National Insititute on Aging, looked at a group of 48 people, all slightly overweight. The subjects were randomly assigned to
one of four groups: calorie restriction, which cut usual daily calories
by 25 percent; calorie restriction plus exercise, which cut daily
calories by 12.5 percent and increased physical activity by 12.5
percent five days a week; very low calories, with an 890-calorie liquid
diet for up to about three months followed by a weight-maintenance
diet; and a control group that aimed to keep weight steady. The Post reports that blood tests showed substantial decreases in the amount of
age-related DNA damage in each of the three dieting groups, compared
with their initial levels, while no changes were seen in the control group. Researchers caution that while the kind of microscopic damage that was slowed by a low calorie diet is linked to cancer and other
age-related ailments, it remains unknown whether the small changes seen
in the study would affect the study volunteers’ disease risks.

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