With Exercise, More Pain, More Gain

June 25, 2014 8:14 am 0 comments

imagesThe question is: if you exercise with greater intensity, will it pay off with stronger muscles and greater endurance? And the answer, according to Gretchen Reynolds in the New York Times, is: it looks that way. Specifically, it looks that way to researchers at the Scripps Research Institute in Florida, who have been studying the function of catecholamines, biochemicals that, as Reynolds writes, “prime the muscles for getaway or battle,” and a protein called CRTC2, also activated during stress. Reynolds reports that the researchers bred mice that were genetically programmed to produce an abundance of CRTC2, then put them on a strenuous treadmill program. The researchers found that the endurance of the specially bred mice increased by 103 percent after two weeks, while the endurance of normal mice on the same program increased only 8.5 percent. The modified mice also had much greater muscle growth. Reynolds tells us that those differences all were the result of a sequence of events set off by catecholamines, which are only released during exercise that the body perceives as stressful. Hence, with no catecholamines, there is no CRTC2, and with no CRTC2, there is no extraordinary endurance or muscle growth. Yes, more pain, more gain. Read more in the New York Times.

Leave a Reply

Recent Posts

  • Pain Sex Exercise May Keep Prostate Cancer Away

    Exercise May Keep Prostate Cancer Away

    Intense exercise, the kind that brings on a good sweat, may help keep prostate cancer at bay. That’s the suggestion of research conducted at the University of California in San Francisco, where scientists tracked tens of thousands of midlife and older men for more than 20 years, noting their healthy lifestyle habits and their incidence of prostate cancer. Ready? The envelope please….the researchers found that vigorous exercise and other healthy lifestyle habits may cut their chances of developing a lethal type of […]

    Read more →
  • Fitness Pain High-Intensity Training Best For Endurance

    High-Intensity Training Best For Endurance

    It seems counterintuitive, but short bursts of high-intensity training appear to do more for endurance than running a marathon does. The Wall Street Journal reports on the research supporting the claim, which was conducted at the Karolinska Institute in Stockholm, where researchers asked 50 men to cycle as fast as possible for 30 seconds, rest for four minutes and then repeat the exercise six times. They then collected muscle tissue samples from the cyclists’ thighs, and looked for evidence of […]

    Read more →
  • Fitness Pain Women's Health Extreme Exercise Could Be Bad For Your Heart

    Extreme Exercise Could Be Bad For Your Heart

    Extreme exercise, such as running more than 35 miles a week or biking more than 150 kilometers a week, could increase levels of coronary artery calcium–a bad thing. The Wall Street Journal reports on a recent study conducted by British physicians that looked at the cardiac health of 169 serious endurance athletes. Forty-one men and 16 women in the group ran more than 35 miles or cycled more than 150 kilometers a week. The researchers found that, compared with the […]

    Read more →
  • Fitness Pain How Many Marathons Should You Run In A Year?

    How Many Marathons Should You Run In A Year?

    For years, the Wall Street Journal tells us, most marathoners thought it wise to limit the number of races run per year to two. Now, however, comes a new school of thought that suggests that running more could be just fine, and good for your finish time. The paper reports that so far in 2015, 15.8 precent of marathon finishers in races tracked by the Active Network ran more than one marathon this year, compared with just 2.3 percent in […]

    Read more →
  • Pain For Dislocated Shoulder, Just Say No To Surgery

    For Dislocated Shoulder, Just Say No To Surgery

    Yes, shoulder dislocations hurt. So does recovery from the surgery that often follows dislocations. Now comes a study from St. Michael’s Hospital in Toronto suggesting that surgery can do more harm than good, by prolonging the recovery period from a shoulder dislocation. Researchers at the hospital studied the progress of 83 patients who suffered moderate or severe shoulder dislocations. Some patients received either plate-and-screws surgery followed by rehabilitation and others had non-surgical treatment with sling and rehabilitation. Ready? the envelope […]

    Read more →
  • Fitness Pain How To Uncramp A Cramped Muscle

    How To Uncramp A Cramped Muscle

    Cramped muscles, as New York Times health columnist Gretchen Reynolds tells us, were long thought to result from dehydration. Not anymore. That supposition was disproved when tests showed that it takes the same amount of small electric shocks administered to muscles of athletes who were dehydrated and athletes who were not to stimulate a cramp. What then does cause a muscle to cramp? Reynolds says recent research suggests that it’s  nerve endings that are overexcited, paradoxically, because they’re tired. What to […]

    Read more →
  • Gear Pain Supplements Send 20,000 To ER Each Year

    Supplements Send 20,000 To ER Each Year

    Dietary supplements send more than 20,000 people to the emergency room every year, according to a study conducted by the Food and Drug Administration and the Centers for Disease Control and Prevention. The New York Times reports on the research, which tracked emergency room visits at a large network of hospitals around the country over a 10-year period. The Times reports that injuries from supplements include allergic reactions, heart trouble, nausea and vomiting, they were largely tied to a variety of […]

    Read more →
  • Pain For Lower Back Pain, Skip Therapy And Keep Moving

    For Lower Back Pain, Skip Therapy And Keep Moving

    How good is physical therapy for lower back pain? Not so good, according to researchers at the University of Utah, who followed more than 200 people with recent-onset low back pain who were randomly assigned to physical therapy or no treatment for the first month after their pain began. HealthDay reports that three months in, the researchers did notice some modest improvement in the ability to move among those who did physical therapy, which included back manipulation and exercise, but after a […]

    Read more →