With Exercise, More Pain, More Gain

June 25, 2014 8:14 am 0 comments

imagesThe question is: if you exercise with greater intensity, will it pay off with stronger muscles and greater endurance? And the answer, according to Gretchen Reynolds in the New York Times, is: it looks that way. Specifically, it looks that way to researchers at the Scripps Research Institute in Florida, who have been studying the function of catecholamines, biochemicals that, as Reynolds writes, “prime the muscles for getaway or battle,” and a protein called CRTC2, also activated during stress. Reynolds reports that the researchers bred mice that were genetically programmed to produce an abundance of CRTC2, then put them on a strenuous treadmill program. The researchers found that the endurance of the specially bred mice increased by 103 percent after two weeks, while the endurance of normal mice on the same program increased only 8.5 percent. The modified mice also had much greater muscle growth. Reynolds tells us that those differences all were the result of a sequence of events set off by catecholamines, which are only released during exercise that the body perceives as stressful. Hence, with no catecholamines, there is no CRTC2, and with no CRTC2, there is no extraordinary endurance or muscle growth. Yes, more pain, more gain. Read more in the New York Times.

Leave a Reply


Recent Posts

  • Pain Women's Health Why Mosquitoes Like You, Or Not

    Why Mosquitoes Like You, Or Not

    There is no scientific evidence that drinking beer keeps mosquitoes away, but does that mean it’s not worth trying? Not at all. Same deal with garlic, which has been proven, at least, to keep other people away. What does keep mosquitoes away? According to researchers at the University of Florida, our genes do, and they also attract mosquitoes. Being thin also seems to dissuade the bugs, as does not being pregnant. And now the news:  A U of Florida news […]

    Read more →
  • Pain This Year’s Ticks Carry Double Whammy

    This Year’s Ticks Carry Double Whammy

    Lyme disease was bad enough, but now, according to disease ecologists at Columbia University, deer ticks have expanded their parasitic payload to include a malaria-like parasite called Babesia microti, which causes babesiosis when transmitted to humans. What’s babesiosis? It’s a lot like Lyme disease, with a flu-like illness, but it can also cause certain types of anemia, and can be fatal in people with suppressed immune systems. And Lyme disease, if left untreated, may lead to problems in the brain and […]

    Read more →
  • Attitude Pain Mindfulness May Ward Off Depression As Well As Drugs

    Mindfulness May Ward Off Depression As Well As Drugs

    What’s better for warding off a relapse of depression: “maintenance antidepressant medication” or mindfulness-based therapy. And the answer is…neither.  Based on the results of a study conducted at the University of Oxford, both practices seem to do the job equally well. Science Daily reports on the research, for which 424 adults with recurrent major depression and taking maintenance antidepressant medication were randomly assigned to come off their medication slowly and receive MBCT (212 participants) or to stay on their medication (212 […]

    Read more →
  • Fitness Gear Pain Muscle-Building Supplements Linked To Cancer

    Muscle-Building Supplements Linked To Cancer

    No, it’s not better to look good than to feel good, especially if looking good requires muscle-building supplements that contain creatine or androstenedione, two additives that may increase the risk of testicular cancer. How do we know? Because a Brown University news release reports that researchers at the school interviewed nearly 900 men, 356 of whom had been diagnosed with testicular germ cell cancer, and 513 who had not, asking not only about their supplement use but also about a wide variety of […]

    Read more →
  • Fitness Pain Many Diet Supplements Contain Dangerous Chemicals

    Many Diet Supplements Contain Dangerous Chemicals

    In December, Canadian authorities banned the sale of diet and workout supplements that contain BMPEA, calling the chemical, which is nearly identical to amphetamine, a “serious health risk.” Curiously, in the United States, the FDA took no such action, even though it had found that nine of 21 supplements tested contained the same chemical as long as two years ago. Strange? It gets more strange. Writing in the New York Times, Anahad O’Connor reports that the federal agency never made […]

    Read more →
  • Fitness Pain No, You Won’t Have A Heart Attack While Exercising, Probably

    No, You Won’t Have A Heart Attack While Exercising, Probably

    The next time your spouse warns you not to push too hard while exercising because you might have a heart attack, remind him or her of the findings of this recent study by the Cedars-Sinai Heart Institute study. Researchers at the institute studied the 1,247 people aged 35-65 from the Portland, Oregon, metropolitan area who had a sudden cardiac arrest between 2002 and 2013. The envelope please… they found that just 5 percent, or 63 people, had a sudden cardiac arrest during […]

    Read more →
  • Gear Pain Women's Health The More You Sweat, The Better You Smell

    The More You Sweat, The Better You Smell

    The more you sweat, the better you smell. That, at least, is the claim of researchers at Queen’s University in Belfast, who have come up with a perfume delivery system that releases more of its aroma when it comes into contact with moisture. Hence, the more you sweat, the more aroma is released, and the better you smell, if you happen to like the aroma. A Queen’s University news release reports that the perfume system also has the ability to remove […]

    Read more →
  • Eating Well Pain Garlic Is Good For Your Brain

    Garlic Is Good For Your Brain

    No. Garlic won’t make you smarter, but according to researchers at the University of Missouri School of Medicine, it might protect your brain against aging and disease. A U of Missouri news release reports that researchers at the school focused on a carbohydrate derivative of garlic known as FruArg and the role this nutrient plays in protective responses, paying particular attention the nutrient’s ability to inhibit ― and even possibly reverse ― brain cell damage caused by environmental stress. What did they […]

    Read more →