Low Vitamin D Linked To Aggressive Prostate Cancer

May 14, 2014 8:32 am 0 comments

imagesFor most people diagnosed with prostate cancer, the condition is something you live with until you die of something else. But sometimes, (10 to 15 percent of cases according to the Harvard School of Public Health), the cancer advances beyond the prostate, and it can turn lethal. Determining which prostate cancer will be aggressive and which will not has been the goal of researchers for more than a decade. Now comes research from Northwestern University suggesting that low levels of vitamin D are a reliable indicator of a greater likelihood that the cancer will be aggressive. A Northwestern new release reports that when researchers looked at the vitamin D levels of 600 men with elevated PSAs or other indicators of prostate cancer, they found that those with severe vitamin D deficiency were more than twice (2.4 times) as likely to have advanced prostate cancer.  Read more from Northwestern University.

Scientists examined data collected from a diverse group of more than 600 men from the Chicago area who had elevated PSA levels or other risk factors for prostate cancer. Each man was screened for vitamin D deficiency before undergoing a prostate biopsy.

The authors were surprised to find that vitamin D deficiency seemed to be a predictor of aggressive forms of prostate cancer diagnosis in African-American and European-American men, even after adjusting for potential confounders including diet, smoking habits, obesity, family history and calcium intake.

“These men, with severe vitamin D deficiency, had greater odds of advanced grade and advanced stage of tumors within or outside the prostate,” Murphy said.

European-American men and African-American men had 3.66 times and 4.89 times increased odds of having aggressive prostate cancer respectively and 2.42 times and 4.22 times increased odds of having tumor stage T2b or higher, respectively.

- See more at: http://www.northwestern.edu/newscenter/stories/2014/04/vitamin-d-deficiency-linked-to-aggressive-prostate-cancer-.html#sthash.WIq1rjSy.dpuf

Scientists examined data collected from a diverse group of more than 600 men from the Chicago area who had elevated PSA levels or other risk factors for prostate cancer. Each man was screened for vitamin D deficiency before undergoing a prostate biopsy.

The authors were surprised to find that vitamin D deficiency seemed to be a predictor of aggressive forms of prostate cancer diagnosis in African-American and European-American men, even after adjusting for potential confounders including diet, smoking habits, obesity, family history and calcium intake.

“These men, with severe vitamin D deficiency, had greater odds of advanced grade and advanced stage of tumors within or outside the prostate,” Murphy said.

European-American men and African-American men had 3.66 times and 4.89 times increased odds of having aggressive prostate cancer respectively and 2.42 times and 4.22 times increased odds of having tumor stage T2b or higher, respectively.

- See more at: http://www.northwestern.edu/newscenter/stories/2014/04/vitamin-d-deficiency-linked-to-aggressive-prostate-cancer-.html#sthash.WIq1rjSy.dpuf

Scientists examined data collected from a diverse group of more than 600 men from the Chicago area who had elevated PSA levels or other risk factors for prostate cancer. Each man was screened for vitamin D deficiency before undergoing a prostate biopsy.

The authors were surprised to find that vitamin D deficiency seemed to be a predictor of aggressive forms of prostate cancer diagnosis in African-American and European-American men, even after adjusting for potential confounders including diet, smoking habits, obesity, family history and calcium intake.

“These men, with severe vitamin D deficiency, had greater odds of advanced grade and advanced stage of tumors within or outside the prostate,” Murphy said.

European-American men and African-American men had 3.66 times and 4.89 times increased odds of having aggressive prostate cancer respectively and 2.42 times and 4.22 times increased odds of having tumor stage T2b or higher, respectively.

- See more at: http://www.northwestern.edu/newscenter/stories/2014/04/vitamin-d-deficiency-linked-to-aggressive-prostate-cancer-.html#sthash.WIq1rjSy.dpuf

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